MTHFR Mutation Test

What makes BiomeIQ's MTHFR Mutation Test Kit so great?

• Test uses a buccal swab making testing easy for any age. 
• Order the test online and have it sent to your home. 
• Easy to understand results. 
• Set up a free 15 minute consultation once you receive your results to get more information and any questions answered. 

Amy Jaramillo talks about the Genetic Test Kit

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MTHFR Test

The MTHFR test is a simple, effective and reliable way to test if you have an MTHFR mutation. Follow us at https://mthfrexperts.com/mthfr-blog/mthfr/

Differences Between the tests

Test Kit

Tests for MTHFR A1298C and MTHFR C677T. This test explains which specific MTHFR mutation you have, and whether you are heterozygous (1 mutation), homozygous (2 mutations), or compound heterozygous (1 copy of A1298C and 1 copy of C677T).

MTHFR + COMT

Tests for both MTHFR A1298C and MTHFR C677T, as well as COMT VAL158MET
If you have both COMT and MTHFR mutations, you are at an increased risk for feeling stressed and anxious. MTHFR mutations create a methylation deficiency. Methylation is essential for many body processes such as healthy neurotransmitter production and breakdown. Methyl groups help the body produce adequate amounts of serotonin, dopamine, and adrenaline. With COMT mutations, you experience slower breakdown speeds of neurotransmitters, and with MTHFR mutations your body is producing fewer neurotransmitters or is unable to properly breakdown neurotransmitters. Having a combination of both of these mutations results in a predisposition to anxiety.

COMT

Tests for COMT VAL158MET.
Finding out whether or not a COMT mutation is affecting your neurotransmitter breakdown, can allow you to choose supplementation that will help improve your symptoms. For example, for individuals with COMT mutations, TMG (Betaine) is often the most effective choice in methyl donor. Therefore, testing for this mutation can help you understand why your body reacts to certain vitamins in negative ways, and you can choose supplementation and nutrition that is right for your genes

Both MTHFR and COMT genes are involved in the methylation pathway and testing their function is important to better understand your body’s functions such as:

• Brain chemistry important for mood, anxiety, and stress
• Immune function
• Controlling inflammation
• Energy production
• Detoxification of chemicals and toxins
• Cardiovascular health

The COMT (catechol-O-methyltransferase)gene codes for the essential COMT enzyme that is involved in the inactivation of catecholamines such as dopamine, epinephrine, norepinephrine, and catechol estrogens. 1-3 Scientific research has demonstrated that a common mutation in the COMT locus results in the replacement of the amino acid valine with methionine at position 158 in the enzyme. This causes a dramatic reduction in the enzyme’s ability to metabolize these neurotransmitters and catechol estrogens

The MTHFR (methylenetetrahydrofolate reductase) gene provides instructions for making an enzyme that helps the body process a type of folate called 5,10-methylenetetrahydrofolate. There are several known mutations of the MTHFR gene, including the C677T and A1298C variants.

The C677T and A1298C variants can each occur in two forms: the normal gene (C677C or A1298A) or a mutated form (C677T or A1298C). The presence of a single mutation (C677T or A1298C) is referred to as a heterozygous mutation. The presence of two mutations (T677T or C1298C) is referred to as a homozygous mutation.

A compound heterozygous mutation occurs when an individual has two different MTHFR mutations, such as C677T and A1298C. This type of mutation is considered more severe than a single heterozygous mutation, as it may result in decreased enzyme activity and an increased risk of certain health problems.

It is important to note that having an MTHFR gene mutation does not necessarily mean that an individual will develop health problems. Many factors, including lifestyle and environmental factors, can impact an individual's risk of developing health problems associated with MTHFR gene mutations. Individuals with MTHFR gene mutations should consult with a healthcare professional for personalized recommendations and to discuss the potential implications of their mutation.

If you have any questions, please sign up for a FREE 15 consultation here

Buccal Swab
Our test kit is minimally invasive, NO blood draw needed. Easy to use, a convenient test that can be performed in the privacy of your home. Designed for all ages including infants. Tests for MTHFR A1298C and MTHFR C677T.

Test Kit includes:

• A Simple Requisition Form
• Two (2) Sterile Buccal Swabs
• Instructions
• Mailing Envelope